Conference Abstract Book

Encapsulation efficiency by HPLC-UV (per curcuminoid) 10 Trial Curcumin (C) % Demethoxy - curcumin (DMC) % Bisdemethoxy -curcumin (BDMC) % T1 97.7 61.3 41.7 T2 76.0 32.4 38.5 T3 72.2 31.4 28.2 T4 38.9 3.1 17.4 T5 50.9 7.6 18.1 T6 96.0 32.5 17.0 • Two-regime optimum for curcumin: Peaks at T1 (1:2; 70:30 WPN:FOS, 97.7%) and T6 (1:4; 30:70, 96.0%)—protein-rich works at low wall load, FOS- rich at high wall load. • Minor curcuminoids differ: DMC crashes in protein-rich 1:4 (T4 = 3.1%) but recovers in FOS- rich 1:4 (T6 = 32.5%); BDMC is highest at low- load, protein-rich (T1/T2) and declines with load. • Formulation tip: For overall curcuminoids use T1- like; if 1:4 is required, choose FOS-rich (T6-like) and consider a small protein bump (~40:60) plus antioxidant/oxygen control to protect BDMC.